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Global Prokaryotic Expression System Market Research Report 2024
Synopsis
The prokaryotic system allows one to obtain large quantities of recombinant proteins in a short time. A simple and inexpensive bacterial cell culture and well-known mechanisms of transcription and translation facilitate the use of these microorganisms.For overproduction of recombinant proteins both eukaryotic and prokaryotic expression systems are used. Choosing the right system depends, among other things, on the growth rate and culture of host cells, level of the target gene expression and posttranslational processing of the synthesized protein. Regardless of the type of expression system, its basic elements are the vector and the expression host. The most widely used system for protein overproduction, both on a laboratory and industrial scale, is the prokaryotic system. This system is based primarily on the bacteria E. coli, although increasingly often Bacillus species are used. The prokaryotic system allows one to obtain large quantities of recombinant proteins in a short time. A simple and inexpensive bacterial cell culture and well-known mechanisms of transcription and translation facilitate the use of these microorganisms. The simplicity of genetic modifications and the availability of many bacterial mutants are additional advantages of the prokaryotic system. In this article we characterize the structural elements of prokaryotic expression vectors. Also strategies for preparation of the target protein gene that increase productivity, facilitate detection and purification of recombinant protein and provide its activity are discussed. Bacterial strains often used as host cells in expression systems as well as the potential location of heterologous proteins are characterized. Knowledge of the basic elements of the prokaryotic expression system allows for production of biologically active proteins in a short time and in satisfactory quantities.
Global Prokaryotic Expression System market is projected to reach US$ 646.2 million in 2029, increasing from US$ 468 million in 2022, with the CAGR of 5.3% during the period of 2023 to 2029. Influencing issues, such as economy environments, COVID-19 and Russia-Ukraine War, have led to great market fluctuations in the past few years and are considered comprehensively in the whole Prokaryotic Expression System market research.
The global prokaryotic expression system market refers to the market for systems and tools used for the expression of proteins in prokaryotic organisms, such as bacteria. Prokaryotic expression systems are widely used in biotechnology and pharmaceutical research for the production of recombinant proteins. The market is driven by several factors. Firstly, the increasing demand for recombinant proteins for research, diagnostics, and therapeutics drives the demand for prokaryotic expression systems. These systems allow for the efficient production of proteins in large quantities, which is essential for various applications in the life sciences. Secondly, the advancements in genetic engineering technologies have led to the development of improved prokaryotic expression systems. These systems enable the expression of complex proteins and facilitate the incorporation of post-translational modifications, enhancing the functionality of the produced proteins. Additionally, the growing investment in biotechnology and pharmaceutical research is fueling the demand for prokaryotic expression systems. Research organizations and pharmaceutical companies are actively engaged in discovering and developing new drugs and biological therapies that rely on recombinant proteins. Prokaryotic expression systems play a vital role in the production of these proteins. Furthermore, the increasing prevalence of chronic diseases, such as cancer and autoimmune disorders, has led to a rise in the demand for protein-based therapeutics. Prokaryotic expression systems offer a cost-effective and scalable solution for the production of these therapeutic proteins. Geographically, the market for prokaryotic expression systems is spread across regions such as North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa. North America dominates the market due to the presence of a well-established biotechnology and pharmaceutical industry. Europe and Asia Pacific follow closely, with significant investments in research and development activities.
Report Scope
This report, based on historical analysis (2018-2022) and forecast calculation (2023-2029), aims to help readers to get a comprehensive understanding of global Prokaryotic Expression System market with multiple angles, which provides sufficient supports to readers’ strategy and decision making.
By Company
Agilent Technologies, Inc.
Bio-Rad Laboratories, Inc.
QIAGEN
Promega Corporation.
Thermo Fischer Scientific, Inc.
Life Technologies Corporation.
Takara Bio Inc.
GenScript
New England Biolabs.
OXFORD EXPRESSION TECHNOLOGIES LTD
LifeSensors, Proteogenix
Synthetic Genomics Inc.
Peak Proteins Ltd
ProMab, Sino Biological Inc.
Lucigen
ARTES Biotechnology GmbH
Jena Bioscience GmbH
BIONEER CORPORATION
LenioBio.
Lonza.
Segment by Type
Fungi
Cell
Others
Segment by Application
Biotech
Medicine
Laboratory
Others
By Region
North America
United States
Canada
Europe
Germany
France
UK
Italy
Russia
Nordic Countries
Rest of Europe
Asia-Pacific
China
Japan
South Korea
Southeast Asia
India
Australia
Rest of Asia
Latin America
Mexico
Brazil
Rest of Latin America
Middle East & Africa
Turkey
Saudi Arabia
UAE
Rest of MEA
The Prokaryotic Expression System report covers below items:
Chapter 1: Product Basic Information (Definition, Type and Application)
Chapter 2: Global market size, regional market size. Market Opportunities and Challenges
Chapter 3: Companies’ Competition Patterns
Chapter 4: Product Type Analysis
Chapter 5: Product Application Analysis
Chapter 6 to 10: Country Level Value Analysis
Chapter 11: Companies’ Outline
Chapter 12: Market Conclusions
Chapter 13: Research Methodology and Data Source
The prokaryotic system allows one to obtain large quantities of recombinant proteins in a short time. A simple and inexpensive bacterial cell culture and well-known mechanisms of transcription and translation facilitate the use of these microorganisms.For overproduction of recombinant proteins both eukaryotic and prokaryotic expression systems are used. Choosing the right system depends, among other things, on the growth rate and culture of host cells, level of the target gene expression and posttranslational processing of the synthesized protein. Regardless of the type of expression system, its basic elements are the vector and the expression host. The most widely used system for protein overproduction, both on a laboratory and industrial scale, is the prokaryotic system. This system is based primarily on the bacteria E. coli, although increasingly often Bacillus species are used. The prokaryotic system allows one to obtain large quantities of recombinant proteins in a short time. A simple and inexpensive bacterial cell culture and well-known mechanisms of transcription and translation facilitate the use of these microorganisms. The simplicity of genetic modifications and the availability of many bacterial mutants are additional advantages of the prokaryotic system. In this article we characterize the structural elements of prokaryotic expression vectors. Also strategies for preparation of the target protein gene that increase productivity, facilitate detection and purification of recombinant protein and provide its activity are discussed. Bacterial strains often used as host cells in expression systems as well as the potential location of heterologous proteins are characterized. Knowledge of the basic elements of the prokaryotic expression system allows for production of biologically active proteins in a short time and in satisfactory quantities.
Global Prokaryotic Expression System market is projected to reach US$ 646.2 million in 2029, increasing from US$ 468 million in 2022, with the CAGR of 5.3% during the period of 2023 to 2029. Influencing issues, such as economy environments, COVID-19 and Russia-Ukraine War, have led to great market fluctuations in the past few years and are considered comprehensively in the whole Prokaryotic Expression System market research.
The global prokaryotic expression system market refers to the market for systems and tools used for the expression of proteins in prokaryotic organisms, such as bacteria. Prokaryotic expression systems are widely used in biotechnology and pharmaceutical research for the production of recombinant proteins. The market is driven by several factors. Firstly, the increasing demand for recombinant proteins for research, diagnostics, and therapeutics drives the demand for prokaryotic expression systems. These systems allow for the efficient production of proteins in large quantities, which is essential for various applications in the life sciences. Secondly, the advancements in genetic engineering technologies have led to the development of improved prokaryotic expression systems. These systems enable the expression of complex proteins and facilitate the incorporation of post-translational modifications, enhancing the functionality of the produced proteins. Additionally, the growing investment in biotechnology and pharmaceutical research is fueling the demand for prokaryotic expression systems. Research organizations and pharmaceutical companies are actively engaged in discovering and developing new drugs and biological therapies that rely on recombinant proteins. Prokaryotic expression systems play a vital role in the production of these proteins. Furthermore, the increasing prevalence of chronic diseases, such as cancer and autoimmune disorders, has led to a rise in the demand for protein-based therapeutics. Prokaryotic expression systems offer a cost-effective and scalable solution for the production of these therapeutic proteins. Geographically, the market for prokaryotic expression systems is spread across regions such as North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa. North America dominates the market due to the presence of a well-established biotechnology and pharmaceutical industry. Europe and Asia Pacific follow closely, with significant investments in research and development activities.
Report Scope
This report, based on historical analysis (2018-2022) and forecast calculation (2023-2029), aims to help readers to get a comprehensive understanding of global Prokaryotic Expression System market with multiple angles, which provides sufficient supports to readers’ strategy and decision making.
By Company
Agilent Technologies, Inc.
Bio-Rad Laboratories, Inc.
QIAGEN
Promega Corporation.
Thermo Fischer Scientific, Inc.
Life Technologies Corporation.
Takara Bio Inc.
GenScript
New England Biolabs.
OXFORD EXPRESSION TECHNOLOGIES LTD
LifeSensors, Proteogenix
Synthetic Genomics Inc.
Peak Proteins Ltd
ProMab, Sino Biological Inc.
Lucigen
ARTES Biotechnology GmbH
Jena Bioscience GmbH
BIONEER CORPORATION
LenioBio.
Lonza.
Segment by Type
Fungi
Cell
Others
Segment by Application
Biotech
Medicine
Laboratory
Others
By Region
North America
United States
Canada
Europe
Germany
France
UK
Italy
Russia
Nordic Countries
Rest of Europe
Asia-Pacific
China
Japan
South Korea
Southeast Asia
India
Australia
Rest of Asia
Latin America
Mexico
Brazil
Rest of Latin America
Middle East & Africa
Turkey
Saudi Arabia
UAE
Rest of MEA
The Prokaryotic Expression System report covers below items:
Chapter 1: Product Basic Information (Definition, Type and Application)
Chapter 2: Global market size, regional market size. Market Opportunities and Challenges
Chapter 3: Companies’ Competition Patterns
Chapter 4: Product Type Analysis
Chapter 5: Product Application Analysis
Chapter 6 to 10: Country Level Value Analysis
Chapter 11: Companies’ Outline
Chapter 12: Market Conclusions
Chapter 13: Research Methodology and Data Source
Index1 Report Overview
1.1 Study Scope
1.2 Market Analysis by Type
1.2.1 Global Prokaryotic Expression System Market Size Growth Rate by Type: 2018 VS 2022 VS 2029
1.2.2 Fungi
1.2.3 Cell
1.2.4 Others
1.3 Market by Application
1.3.1 Global Prokaryotic Expression System Market Growth by Application: 2018 VS 2022 VS 2029
1.3.2 Biotech
1.3.3 Medicine
1.3.4 Laboratory
1.3.5 Others
1.4 Study Objectives
1.5 Years Considered
1.6 Years Considered
2 Global Growth Trends
2.1 Global Prokaryotic Expression System Market Perspective (2018-2029)
2.2 Prokaryotic Expression System Growth Trends by Region
2.2.1 Global Prokaryotic Expression System Market Size by Region: 2018 VS 2022 VS 2029
2.2.2 Prokaryotic Expression System Historic Market Size by Region (2018-2023)
2.2.3 Prokaryotic Expression System Forecasted Market Size by Region (2024-2029)
2.3 Prokaryotic Expression System Market Dynamics
2.3.1 Prokaryotic Expression System Industry Trends
2.3.2 Prokaryotic Expression System Market Drivers
2.3.3 Prokaryotic Expression System Market Challenges
2.3.4 Prokaryotic Expression System Market Restraints
3 Competition Landscape by Key Players
3.1 Global Top Prokaryotic Expression System Players by Revenue
3.1.1 Global Top Prokaryotic Expression System Players by Revenue (2018-2023)
3.1.2 Global Prokaryotic Expression System Revenue Market Share by Players (2018-2023)
3.2 Global Prokaryotic Expression System Market Share by Company Type (Tier 1, Tier 2, and Tier 3)
3.3 Players Covered: Ranking by Prokaryotic Expression System Revenue
3.4 Global Prokaryotic Expression System Market Concentration Ratio
3.4.1 Global Prokaryotic Expression System Market Concentration Ratio (CR5 and HHI)
3.4.2 Global Top 10 and Top 5 Companies by Prokaryotic Expression System Revenue in 2022
3.5 Prokaryotic Expression System Key Players Head office and Area Served
3.6 Key Players Prokaryotic Expression System Product Solution and Service
3.7 Date of Enter into Prokaryotic Expression System Market
3.8 Mergers & Acquisitions, Expansion Plans
4 Prokaryotic Expression System Breakdown Data by Type
4.1 Global Prokaryotic Expression System Historic Market Size by Type (2018-2023)
4.2 Global Prokaryotic Expression System Forecasted Market Size by Type (2024-2029)
5 Prokaryotic Expression System Breakdown Data by Application
5.1 Global Prokaryotic Expression System Historic Market Size by Application (2018-2023)
5.2 Global Prokaryotic Expression System Forecasted Market Size by Application (2024-2029)
6 North America
6.1 North America Prokaryotic Expression System Market Size (2018-2029)
6.2 North America Prokaryotic Expression System Market Growth Rate by Country: 2018 VS 2022 VS 2029
6.3 North America Prokaryotic Expression System Market Size by Country (2018-2023)
6.4 North America Prokaryotic Expression System Market Size by Country (2024-2029)
6.5 United States
6.6 Canada
7 Europe
7.1 Europe Prokaryotic Expression System Market Size (2018-2029)
7.2 Europe Prokaryotic Expression System Market Growth Rate by Country: 2018 VS 2022 VS 2029
7.3 Europe Prokaryotic Expression System Market Size by Country (2018-2023)
7.4 Europe Prokaryotic Expression System Market Size by Country (2024-2029)
7.5 Germany
7.6 France
7.7 U.K.
7.8 Italy
7.9 Russia
7.10 Nordic Countries
8 Asia-Pacific
8.1 Asia-Pacific Prokaryotic Expression System Market Size (2018-2029)
8.2 Asia-Pacific Prokaryotic Expression System Market Growth Rate by Region: 2018 VS 2022 VS 2029
8.3 Asia-Pacific Prokaryotic Expression System Market Size by Region (2018-2023)
8.4 Asia-Pacific Prokaryotic Expression System Market Size by Region (2024-2029)
8.5 China
8.6 Japan
8.7 South Korea
8.8 Southeast Asia
8.9 India
8.10 Australia
9 Latin America
9.1 Latin America Prokaryotic Expression System Market Size (2018-2029)
9.2 Latin America Prokaryotic Expression System Market Growth Rate by Country: 2018 VS 2022 VS 2029
9.3 Latin America Prokaryotic Expression System Market Size by Country (2018-2023)
9.4 Latin America Prokaryotic Expression System Market Size by Country (2024-2029)
9.5 Mexico
9.6 Brazil
10 Middle East & Africa
10.1 Middle East & Africa Prokaryotic Expression System Market Size (2018-2029)
10.2 Middle East & Africa Prokaryotic Expression System Market Growth Rate by Country: 2018 VS 2022 VS 2029
10.3 Middle East & Africa Prokaryotic Expression System Market Size by Country (2018-2023)
10.4 Middle East & Africa Prokaryotic Expression System Market Size by Country (2024-2029)
10.5 Turkey
10.6 Saudi Arabia
10.7 UAE
11 Key Players Profiles
11.1 Agilent Technologies, Inc.
11.1.1 Agilent Technologies, Inc. Company Detail
11.1.2 Agilent Technologies, Inc. Business Overview
11.1.3 Agilent Technologies, Inc. Prokaryotic Expression System Introduction
11.1.4 Agilent Technologies, Inc. Revenue in Prokaryotic Expression System Business (2018-2023)
11.1.5 Agilent Technologies, Inc. Recent Development
11.2 Bio-Rad Laboratories, Inc.
11.2.1 Bio-Rad Laboratories, Inc. Company Detail
11.2.2 Bio-Rad Laboratories, Inc. Business Overview
11.2.3 Bio-Rad Laboratories, Inc. Prokaryotic Expression System Introduction
11.2.4 Bio-Rad Laboratories, Inc. Revenue in Prokaryotic Expression System Business (2018-2023)
11.2.5 Bio-Rad Laboratories, Inc. Recent Development
11.3 QIAGEN
11.3.1 QIAGEN Company Detail
11.3.2 QIAGEN Business Overview
11.3.3 QIAGEN Prokaryotic Expression System Introduction
11.3.4 QIAGEN Revenue in Prokaryotic Expression System Business (2018-2023)
11.3.5 QIAGEN Recent Development
11.4 Promega Corporation.
11.4.1 Promega Corporation. Company Detail
11.4.2 Promega Corporation. Business Overview
11.4.3 Promega Corporation. Prokaryotic Expression System Introduction
11.4.4 Promega Corporation. Revenue in Prokaryotic Expression System Business (2018-2023)
11.4.5 Promega Corporation. Recent Development
11.5 Thermo Fischer Scientific, Inc.
11.5.1 Thermo Fischer Scientific, Inc. Company Detail
11.5.2 Thermo Fischer Scientific, Inc. Business Overview
11.5.3 Thermo Fischer Scientific, Inc. Prokaryotic Expression System Introduction
11.5.4 Thermo Fischer Scientific, Inc. Revenue in Prokaryotic Expression System Business (2018-2023)
11.5.5 Thermo Fischer Scientific, Inc. Recent Development
11.6 Life Technologies Corporation.
11.6.1 Life Technologies Corporation. Company Detail
11.6.2 Life Technologies Corporation. Business Overview
11.6.3 Life Technologies Corporation. Prokaryotic Expression System Introduction
11.6.4 Life Technologies Corporation. Revenue in Prokaryotic Expression System Business (2018-2023)
11.6.5 Life Technologies Corporation. Recent Development
11.7 Takara Bio Inc.
11.7.1 Takara Bio Inc. Company Detail
11.7.2 Takara Bio Inc. Business Overview
11.7.3 Takara Bio Inc. Prokaryotic Expression System Introduction
11.7.4 Takara Bio Inc. Revenue in Prokaryotic Expression System Business (2018-2023)
11.7.5 Takara Bio Inc. Recent Development
11.8 GenScript
11.8.1 GenScript Company Detail
11.8.2 GenScript Business Overview
11.8.3 GenScript Prokaryotic Expression System Introduction
11.8.4 GenScript Revenue in Prokaryotic Expression System Business (2018-2023)
11.8.5 GenScript Recent Development
11.9 New England Biolabs.
11.9.1 New England Biolabs. Company Detail
11.9.2 New England Biolabs. Business Overview
11.9.3 New England Biolabs. Prokaryotic Expression System Introduction
11.9.4 New England Biolabs. Revenue in Prokaryotic Expression System Business (2018-2023)
11.9.5 New England Biolabs. Recent Development
11.10 OXFORD EXPRESSION TECHNOLOGIES LTD
11.10.1 OXFORD EXPRESSION TECHNOLOGIES LTD Company Detail
11.10.2 OXFORD EXPRESSION TECHNOLOGIES LTD Business Overview
11.10.3 OXFORD EXPRESSION TECHNOLOGIES LTD Prokaryotic Expression System Introduction
11.10.4 OXFORD EXPRESSION TECHNOLOGIES LTD Revenue in Prokaryotic Expression System Business (2018-2023)
11.10.5 OXFORD EXPRESSION TECHNOLOGIES LTD Recent Development
11.11 LifeSensors, Proteogenix
11.11.1 LifeSensors, Proteogenix Company Detail
11.11.2 LifeSensors, Proteogenix Business Overview
11.11.3 LifeSensors, Proteogenix Prokaryotic Expression System Introduction
11.11.4 LifeSensors, Proteogenix Revenue in Prokaryotic Expression System Business (2018-2023)
11.11.5 LifeSensors, Proteogenix Recent Development
11.12 Synthetic Genomics Inc.
11.12.1 Synthetic Genomics Inc. Company Detail
11.12.2 Synthetic Genomics Inc. Business Overview
11.12.3 Synthetic Genomics Inc. Prokaryotic Expression System Introduction
11.12.4 Synthetic Genomics Inc. Revenue in Prokaryotic Expression System Business (2018-2023)
11.12.5 Synthetic Genomics Inc. Recent Development
11.13 Peak Proteins Ltd
11.13.1 Peak Proteins Ltd Company Detail
11.13.2 Peak Proteins Ltd Business Overview
11.13.3 Peak Proteins Ltd Prokaryotic Expression System Introduction
11.13.4 Peak Proteins Ltd Revenue in Prokaryotic Expression System Business (2018-2023)
11.13.5 Peak Proteins Ltd Recent Development
11.14 ProMab, Sino Biological Inc.
11.14.1 ProMab, Sino Biological Inc. Company Detail
11.14.2 ProMab, Sino Biological Inc. Business Overview
11.14.3 ProMab, Sino Biological Inc. Prokaryotic Expression System Introduction
11.14.4 ProMab, Sino Biological Inc. Revenue in Prokaryotic Expression System Business (2018-2023)
11.14.5 ProMab, Sino Biological Inc. Recent Development
11.15 Lucigen
11.15.1 Lucigen Company Detail
11.15.2 Lucigen Business Overview
11.15.3 Lucigen Prokaryotic Expression System Introduction
11.15.4 Lucigen Revenue in Prokaryotic Expression System Business (2018-2023)
11.15.5 Lucigen Recent Development
11.16 ARTES Biotechnology GmbH
11.16.1 ARTES Biotechnology GmbH Company Detail
11.16.2 ARTES Biotechnology GmbH Business Overview
11.16.3 ARTES Biotechnology GmbH Prokaryotic Expression System Introduction
11.16.4 ARTES Biotechnology GmbH Revenue in Prokaryotic Expression System Business (2018-2023)
11.16.5 ARTES Biotechnology GmbH Recent Development
11.17 Jena Bioscience GmbH
11.17.1 Jena Bioscience GmbH Company Detail
11.17.2 Jena Bioscience GmbH Business Overview
11.17.3 Jena Bioscience GmbH Prokaryotic Expression System Introduction
11.17.4 Jena Bioscience GmbH Revenue in Prokaryotic Expression System Business (2018-2023)
11.17.5 Jena Bioscience GmbH Recent Development
11.18 BIONEER CORPORATION
11.18.1 BIONEER CORPORATION Company Detail
11.18.2 BIONEER CORPORATION Business Overview
11.18.3 BIONEER CORPORATION Prokaryotic Expression System Introduction
11.18.4 BIONEER CORPORATION Revenue in Prokaryotic Expression System Business (2018-2023)
11.18.5 BIONEER CORPORATION Recent Development
11.19 LenioBio.
11.19.1 LenioBio. Company Detail
11.19.2 LenioBio. Business Overview
11.19.3 LenioBio. Prokaryotic Expression System Introduction
11.19.4 LenioBio. Revenue in Prokaryotic Expression System Business (2018-2023)
11.19.5 LenioBio. Recent Development
11.20 Lonza.
11.20.1 Lonza. Company Detail
11.20.2 Lonza. Business Overview
11.20.3 Lonza. Prokaryotic Expression System Introduction
11.20.4 Lonza. Revenue in Prokaryotic Expression System Business (2018-2023)
11.20.5 Lonza. Recent Development
12 Analyst's Viewpoints/Conclusions
13 Appendix
13.1 Research Methodology
13.1.1 Methodology/Research Approach
13.1.2 Data Source
13.2 Disclaimer
13.3 Author Details
Published By : QY Research
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