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Global Protein Degradation Therapy Market Research Report 2025
Synopsis
Targeted protein degradation (TPD) has surfaced as a novel and innovative chemical tool and therapeutic modality. By co-opting protein degradation pathways, TPD facilitates complete removal of the protein molecules from within or outside the cell. While the pioneering Proteolysis-Targeting Chimera (PROTAC) technology and molecular glues hijack the ubiquitin-proteasome system, newer modalities co-opt autophagy or the endo-lysosomal pathway.
The global Protein Degradation Therapy market was valued at US$ 1132 million in 2023 and is anticipated to reach US$ 1821.4 million by 2030, witnessing a CAGR of 6.3% during the forecast period 2024-2030.
The Protein Degradation Therapy market has gained momentum as a promising approach in drug development. This innovative strategy aims to target disease-causing proteins by facilitating their degradation within cells. Proteins that contribute to diseases like cancer and neurodegenerative disorders can be selectively broken down using small molecules known as proteolysis-targeting chimeras (PROTACs) or other protein degraders. This approach offers advantages over traditional inhibition methods, potentially leading to more effective treatments with reduced side effects. As researchers delve into protein-protein interactions and cellular mechanisms, the Protein Degradation Therapy market is expanding, presenting opportunities to address previously challenging diseases and advance precision medicine. Clinical progress and continued research in this field are expected to shape the future of therapeutic interventions.
This report aims to provide a comprehensive presentation of the global market for Protein Degradation Therapy, with both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding Protein Degradation Therapy.
Report Scope
The Protein Degradation Therapy market size, estimations, and forecasts are provided in terms of revenue ($ millions), considering 2023 as the base year, with history and forecast data for the period from 2019 to 2030. This report segments the global Protein Degradation Therapy market comprehensively. Regional market sizes, concerning products by Type, by Application, and by players, are also provided.
For a more in-depth understanding of the market, the report provides profiles of the competitive landscape, key competitors, and their respective market ranks. The report also discusses technological trends and new product developments.
The report will help the Protein Degradation Therapy companies, new entrants, and industry chain related companies in this market with information on the revenues, sales volume, and average price for the overall market and the sub-segments across the different segments, by company, by Type, by Application, and by regions.
Market Segmentation
By Company
Arvinas
Nurix Therapeutics
Kymera Therapeutics
C4 Therapeutics
Segment by Type
ARV-110
ARV-471
Other
Segment by Application
Cancer
Neuroscience
Other
By Region
North America
United States
Canada
Europe
Germany
France
UK
Italy
Russia
Nordic Countries
Rest of Europe
Asia-Pacific
China
Japan
South Korea
Southeast Asia
India
Australia
Rest of Asia
Latin America
Mexico
Brazil
Rest of Latin America
Middle East & Africa
Turkey
Saudi Arabia
UAE
Rest of MEA
Chapter Outline
Chapter 1: Introduces the report scope of the report, executive summary of different market segments (by Type, by Application, etc), including the market size of each market segment, future development potential, and so on. It offers a high-level view of the current state of the market and its likely evolution in the short to mid-term, and long term.
Chapter 2: Introduces executive summary of global market size, regional market size, this section also introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by companies in the industry, and the analysis of relevant policies in the industry.
Chapter 3: Detailed analysis of Protein Degradation Therapy companies’ competitive landscape, revenue market share, latest development plan, merger, and acquisition information, etc.
Chapter 4: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 5: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 6, 7, 8, 9, 10: North America, Europe, Asia Pacific, Latin America, Middle East and Africa segment by country. It provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development, future development prospects, market space, and capacity of each country in the world.
Chapter 11: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter 12: The main points and conclusions of the report.
Targeted protein degradation (TPD) has surfaced as a novel and innovative chemical tool and therapeutic modality. By co-opting protein degradation pathways, TPD facilitates complete removal of the protein molecules from within or outside the cell. While the pioneering Proteolysis-Targeting Chimera (PROTAC) technology and molecular glues hijack the ubiquitin-proteasome system, newer modalities co-opt autophagy or the endo-lysosomal pathway.
The global Protein Degradation Therapy market was valued at US$ 1132 million in 2023 and is anticipated to reach US$ 1821.4 million by 2030, witnessing a CAGR of 6.3% during the forecast period 2024-2030.
The Protein Degradation Therapy market has gained momentum as a promising approach in drug development. This innovative strategy aims to target disease-causing proteins by facilitating their degradation within cells. Proteins that contribute to diseases like cancer and neurodegenerative disorders can be selectively broken down using small molecules known as proteolysis-targeting chimeras (PROTACs) or other protein degraders. This approach offers advantages over traditional inhibition methods, potentially leading to more effective treatments with reduced side effects. As researchers delve into protein-protein interactions and cellular mechanisms, the Protein Degradation Therapy market is expanding, presenting opportunities to address previously challenging diseases and advance precision medicine. Clinical progress and continued research in this field are expected to shape the future of therapeutic interventions.
This report aims to provide a comprehensive presentation of the global market for Protein Degradation Therapy, with both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding Protein Degradation Therapy.
Report Scope
The Protein Degradation Therapy market size, estimations, and forecasts are provided in terms of revenue ($ millions), considering 2023 as the base year, with history and forecast data for the period from 2019 to 2030. This report segments the global Protein Degradation Therapy market comprehensively. Regional market sizes, concerning products by Type, by Application, and by players, are also provided.
For a more in-depth understanding of the market, the report provides profiles of the competitive landscape, key competitors, and their respective market ranks. The report also discusses technological trends and new product developments.
The report will help the Protein Degradation Therapy companies, new entrants, and industry chain related companies in this market with information on the revenues, sales volume, and average price for the overall market and the sub-segments across the different segments, by company, by Type, by Application, and by regions.
Market Segmentation
By Company
Arvinas
Nurix Therapeutics
Kymera Therapeutics
C4 Therapeutics
Segment by Type
ARV-110
ARV-471
Other
Segment by Application
Cancer
Neuroscience
Other
By Region
North America
United States
Canada
Europe
Germany
France
UK
Italy
Russia
Nordic Countries
Rest of Europe
Asia-Pacific
China
Japan
South Korea
Southeast Asia
India
Australia
Rest of Asia
Latin America
Mexico
Brazil
Rest of Latin America
Middle East & Africa
Turkey
Saudi Arabia
UAE
Rest of MEA
Chapter Outline
Chapter 1: Introduces the report scope of the report, executive summary of different market segments (by Type, by Application, etc), including the market size of each market segment, future development potential, and so on. It offers a high-level view of the current state of the market and its likely evolution in the short to mid-term, and long term.
Chapter 2: Introduces executive summary of global market size, regional market size, this section also introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by companies in the industry, and the analysis of relevant policies in the industry.
Chapter 3: Detailed analysis of Protein Degradation Therapy companies’ competitive landscape, revenue market share, latest development plan, merger, and acquisition information, etc.
Chapter 4: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 5: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 6, 7, 8, 9, 10: North America, Europe, Asia Pacific, Latin America, Middle East and Africa segment by country. It provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development, future development prospects, market space, and capacity of each country in the world.
Chapter 11: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter 12: The main points and conclusions of the report.
Index1 Report Overview
1.1 Study Scope
1.2 Market Analysis by Type
1.2.1 Global Protein Degradation Therapy Market Size Growth Rate by Type: 2019 VS 2023 VS 2030
1.2.2 ARV-110
1.2.3 ARV-471
1.2.4 Other
1.3 Market by Application
1.3.1 Global Protein Degradation Therapy Market Growth by Application: 2019 VS 2023 VS 2030
1.3.2 Cancer
1.3.3 Neuroscience
1.3.4 Other
1.4 Study Objectives
1.5 Years Considered
1.6 Years Considered
2 Global Growth Trends
2.1 Global Protein Degradation Therapy Market Perspective (2019-2030)
2.2 Protein Degradation Therapy Growth Trends by Region
2.2.1 Global Protein Degradation Therapy Market Size by Region: 2019 VS 2023 VS 2030
2.2.2 Protein Degradation Therapy Historic Market Size by Region (2019-2024)
2.2.3 Protein Degradation Therapy Forecasted Market Size by Region (2025-2030)
2.3 Protein Degradation Therapy Market Dynamics
2.3.1 Protein Degradation Therapy Industry Trends
2.3.2 Protein Degradation Therapy Market Drivers
2.3.3 Protein Degradation Therapy Market Challenges
2.3.4 Protein Degradation Therapy Market Restraints
3 Competition Landscape by Key Players
3.1 Global Top Protein Degradation Therapy Players by Revenue
3.1.1 Global Top Protein Degradation Therapy Players by Revenue (2019-2024)
3.1.2 Global Protein Degradation Therapy Revenue Market Share by Players (2019-2024)
3.2 Global Protein Degradation Therapy Market Share by Company Type (Tier 1, Tier 2, and Tier 3)
3.3 Players Covered: Ranking by Protein Degradation Therapy Revenue
3.4 Global Protein Degradation Therapy Market Concentration Ratio
3.4.1 Global Protein Degradation Therapy Market Concentration Ratio (CR5 and HHI)
3.4.2 Global Top 10 and Top 5 Companies by Protein Degradation Therapy Revenue in 2023
3.5 Protein Degradation Therapy Key Players Head office and Area Served
3.6 Key Players Protein Degradation Therapy Product Solution and Service
3.7 Date of Enter into Protein Degradation Therapy Market
3.8 Mergers & Acquisitions, Expansion Plans
4 Protein Degradation Therapy Breakdown Data by Type
4.1 Global Protein Degradation Therapy Historic Market Size by Type (2019-2024)
4.2 Global Protein Degradation Therapy Forecasted Market Size by Type (2025-2030)
5 Protein Degradation Therapy Breakdown Data by Application
5.1 Global Protein Degradation Therapy Historic Market Size by Application (2019-2024)
5.2 Global Protein Degradation Therapy Forecasted Market Size by Application (2025-2030)
6 North America
6.1 North America Protein Degradation Therapy Market Size (2019-2030)
6.2 North America Protein Degradation Therapy Market Growth Rate by Country: 2019 VS 2023 VS 2030
6.3 North America Protein Degradation Therapy Market Size by Country (2019-2024)
6.4 North America Protein Degradation Therapy Market Size by Country (2025-2030)
6.5 United States
6.6 Canada
7 Europe
7.1 Europe Protein Degradation Therapy Market Size (2019-2030)
7.2 Europe Protein Degradation Therapy Market Growth Rate by Country: 2019 VS 2023 VS 2030
7.3 Europe Protein Degradation Therapy Market Size by Country (2019-2024)
7.4 Europe Protein Degradation Therapy Market Size by Country (2025-2030)
7.5 Germany
7.6 France
7.7 U.K.
7.8 Italy
7.9 Russia
7.10 Nordic Countries
8 Asia-Pacific
8.1 Asia-Pacific Protein Degradation Therapy Market Size (2019-2030)
8.2 Asia-Pacific Protein Degradation Therapy Market Growth Rate by Region: 2019 VS 2023 VS 2030
8.3 Asia-Pacific Protein Degradation Therapy Market Size by Region (2019-2024)
8.4 Asia-Pacific Protein Degradation Therapy Market Size by Region (2025-2030)
8.5 China
8.6 Japan
8.7 South Korea
8.8 Southeast Asia
8.9 India
8.10 Australia
9 Latin America
9.1 Latin America Protein Degradation Therapy Market Size (2019-2030)
9.2 Latin America Protein Degradation Therapy Market Growth Rate by Country: 2019 VS 2023 VS 2030
9.3 Latin America Protein Degradation Therapy Market Size by Country (2019-2024)
9.4 Latin America Protein Degradation Therapy Market Size by Country (2025-2030)
9.5 Mexico
9.6 Brazil
10 Middle East & Africa
10.1 Middle East & Africa Protein Degradation Therapy Market Size (2019-2030)
10.2 Middle East & Africa Protein Degradation Therapy Market Growth Rate by Country: 2019 VS 2023 VS 2030
10.3 Middle East & Africa Protein Degradation Therapy Market Size by Country (2019-2024)
10.4 Middle East & Africa Protein Degradation Therapy Market Size by Country (2025-2030)
10.5 Turkey
10.6 Saudi Arabia
10.7 UAE
11 Key Players Profiles
11.1 Arvinas
11.1.1 Arvinas Company Detail
11.1.2 Arvinas Business Overview
11.1.3 Arvinas Protein Degradation Therapy Introduction
11.1.4 Arvinas Revenue in Protein Degradation Therapy Business (2019-2024)
11.1.5 Arvinas Recent Development
11.2 Nurix Therapeutics
11.2.1 Nurix Therapeutics Company Detail
11.2.2 Nurix Therapeutics Business Overview
11.2.3 Nurix Therapeutics Protein Degradation Therapy Introduction
11.2.4 Nurix Therapeutics Revenue in Protein Degradation Therapy Business (2019-2024)
11.2.5 Nurix Therapeutics Recent Development
11.3 Kymera Therapeutics
11.3.1 Kymera Therapeutics Company Detail
11.3.2 Kymera Therapeutics Business Overview
11.3.3 Kymera Therapeutics Protein Degradation Therapy Introduction
11.3.4 Kymera Therapeutics Revenue in Protein Degradation Therapy Business (2019-2024)
11.3.5 Kymera Therapeutics Recent Development
11.4 C4 Therapeutics
11.4.1 C4 Therapeutics Company Detail
11.4.2 C4 Therapeutics Business Overview
11.4.3 C4 Therapeutics Protein Degradation Therapy Introduction
11.4.4 C4 Therapeutics Revenue in Protein Degradation Therapy Business (2019-2024)
11.4.5 C4 Therapeutics Recent Development
12 Analyst's Viewpoints/Conclusions
13 Appendix
13.1 Research Methodology
13.1.1 Methodology/Research Approach
13.1.2 Data Source
13.2 Disclaimer
13.3 Author Details
Published By : QY Research
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