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Global Vertebroplasty and Kyphoplasty Device Market Research Report 2024
Synopsis
Vertebroplasty & Kyphoplasty are minimally invasive, image guided surgical procedures performed to treat the Vertebral Compression Fracture (VCF). VCFs can lead to back pain, reduced physical activity, depression, loss of independence, decreased lung capacity, and difficulty sleeping. Bone cement is injected into the back bone (vertebra) to provide support to the broken bone. Due to osteoporosis, vascular malformatins or, less commonly, cancer fractures can be caused in the vertebra. Vertebroplasty & Kyphoplasty help the patient to regain the functional abilities and avoid further vertebral collapse. Kyphoplasty is an advanced version of Vertebroplasty which can stabilize the fracture, restore heights and reduce deformities. The report studies the vertebroplasty and kyphoplasty devices market.
The global Vertebroplasty and Kyphoplasty Device market was valued at US$ 1234 million in 2023 and is anticipated to reach US$ 1571.4 million by 2030, witnessing a CAGR of 3.4% during the forecast period 2024-2030.
Global Vertebroplasty and Kyphoplasty Devices key players include Medtronic, Stryker, J&J (Depuy Synthes), Globus Medical, Merit Medical, etc. Global top five manufacturers hold a share about 85%. North America is the largest market, with a share about 55%, followed by Asia-Pacific, with a share about 25 percent. In terms of product, Kyphoplasty is the largest segment, with a share about 80%. And in terms of application, the largest application is Hospital, followed by Ambulatory Surgery Center, etc.
This report aims to provide a comprehensive presentation of the global market for Vertebroplasty and Kyphoplasty Device, with both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding Vertebroplasty and Kyphoplasty Device.
Report Scope
The Vertebroplasty and Kyphoplasty Device market size, estimations, and forecasts are provided in terms of sales volume (K Units) and revenue ($ millions), considering 2023 as the base year, with history and forecast data for the period from 2019 to 2030. This report segments the global Vertebroplasty and Kyphoplasty Device market comprehensively. Regional market sizes, concerning products by Type, by Application, and by players, are also provided.
For a more in-depth understanding of the market, the report provides profiles of the competitive landscape, key competitors, and their respective market ranks. The report also discusses technological trends and new product developments.
The report will help the Vertebroplasty and Kyphoplasty Device manufacturers, new entrants, and industry chain related companies in this market with information on the revenues, sales volume, and average price for the overall market and the sub-segments across the different segments, by company, by Type, by Application, and by regions.
Market Segmentation
By Company
Medtronic
Stryker
DePuy Synthes (Johnson & Johnson)
Globus Medical
Merit Medical Systems
BMK Global Medical Company
IZI Medial Products
Zavation
G21 Srl
Joline
Spine Wave
Teknimed
PanMed
Biopsybell
Segment by Type
Needles
Balloons
Cement Mixing and Delivery Devices
Segment by Application
Hospital
Ambulatory Surgery Center
Others
Consumption by Region
North America
U.S.
Canada
Europe
Germany
France
U.K.
Italy
Russia
Asia-Pacific
China
Japan
South Korea
India
Australia
China Taiwan
Indonesia
Thailand
Malaysia
Latin America
Mexico
Brazil
Argentina
Middle East & Africa
Turkey
Saudi Arabia
UAE
Chapter Outline
Chapter 1: Introduces the report scope of the report, executive summary of different market segments (by region, by Type, by Application, etc), including the market size of each market segment, future development potential, and so on. It offers a high-level view of the current state of the market and its likely evolution in the short to mid-term, and long term.
Chapter 2: Detailed analysis of Vertebroplasty and Kyphoplasty Device manufacturers competitive landscape, price, sales and revenue market share, latest development plan, merger, and acquisition information, etc.
Chapter 3: Sales, revenue of Vertebroplasty and Kyphoplasty Device in regional level and country level. It provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development, future development prospects, market space, and market size of each country in the world.
Chapter 4: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 5: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 6: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter 7: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 8: Introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 9: The main points and conclusions of the report.
Vertebroplasty & Kyphoplasty are minimally invasive, image guided surgical procedures performed to treat the Vertebral Compression Fracture (VCF). VCFs can lead to back pain, reduced physical activity, depression, loss of independence, decreased lung capacity, and difficulty sleeping. Bone cement is injected into the back bone (vertebra) to provide support to the broken bone. Due to osteoporosis, vascular malformatins or, less commonly, cancer fractures can be caused in the vertebra. Vertebroplasty & Kyphoplasty help the patient to regain the functional abilities and avoid further vertebral collapse. Kyphoplasty is an advanced version of Vertebroplasty which can stabilize the fracture, restore heights and reduce deformities. The report studies the vertebroplasty and kyphoplasty devices market.
The global Vertebroplasty and Kyphoplasty Device market was valued at US$ 1234 million in 2023 and is anticipated to reach US$ 1571.4 million by 2030, witnessing a CAGR of 3.4% during the forecast period 2024-2030.
Global Vertebroplasty and Kyphoplasty Devices key players include Medtronic, Stryker, J&J (Depuy Synthes), Globus Medical, Merit Medical, etc. Global top five manufacturers hold a share about 85%. North America is the largest market, with a share about 55%, followed by Asia-Pacific, with a share about 25 percent. In terms of product, Kyphoplasty is the largest segment, with a share about 80%. And in terms of application, the largest application is Hospital, followed by Ambulatory Surgery Center, etc.
This report aims to provide a comprehensive presentation of the global market for Vertebroplasty and Kyphoplasty Device, with both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding Vertebroplasty and Kyphoplasty Device.
Report Scope
The Vertebroplasty and Kyphoplasty Device market size, estimations, and forecasts are provided in terms of sales volume (K Units) and revenue ($ millions), considering 2023 as the base year, with history and forecast data for the period from 2019 to 2030. This report segments the global Vertebroplasty and Kyphoplasty Device market comprehensively. Regional market sizes, concerning products by Type, by Application, and by players, are also provided.
For a more in-depth understanding of the market, the report provides profiles of the competitive landscape, key competitors, and their respective market ranks. The report also discusses technological trends and new product developments.
The report will help the Vertebroplasty and Kyphoplasty Device manufacturers, new entrants, and industry chain related companies in this market with information on the revenues, sales volume, and average price for the overall market and the sub-segments across the different segments, by company, by Type, by Application, and by regions.
Market Segmentation
By Company
Medtronic
Stryker
DePuy Synthes (Johnson & Johnson)
Globus Medical
Merit Medical Systems
BMK Global Medical Company
IZI Medial Products
Zavation
G21 Srl
Joline
Spine Wave
Teknimed
PanMed
Biopsybell
Segment by Type
Needles
Balloons
Cement Mixing and Delivery Devices
Segment by Application
Hospital
Ambulatory Surgery Center
Others
Consumption by Region
North America
U.S.
Canada
Europe
Germany
France
U.K.
Italy
Russia
Asia-Pacific
China
Japan
South Korea
India
Australia
China Taiwan
Indonesia
Thailand
Malaysia
Latin America
Mexico
Brazil
Argentina
Middle East & Africa
Turkey
Saudi Arabia
UAE
Chapter Outline
Chapter 1: Introduces the report scope of the report, executive summary of different market segments (by region, by Type, by Application, etc), including the market size of each market segment, future development potential, and so on. It offers a high-level view of the current state of the market and its likely evolution in the short to mid-term, and long term.
Chapter 2: Detailed analysis of Vertebroplasty and Kyphoplasty Device manufacturers competitive landscape, price, sales and revenue market share, latest development plan, merger, and acquisition information, etc.
Chapter 3: Sales, revenue of Vertebroplasty and Kyphoplasty Device in regional level and country level. It provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development, future development prospects, market space, and market size of each country in the world.
Chapter 4: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 5: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 6: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter 7: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 8: Introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 9: The main points and conclusions of the report.
Index1 Vertebroplasty and Kyphoplasty Device Market Overview
1.1 Product Overview and Scope of Vertebroplasty and Kyphoplasty Device
1.2 Vertebroplasty and Kyphoplasty Device Segment by Type
1.2.1 Global Vertebroplasty and Kyphoplasty Device Market Value Comparison by Type (2024-2030)
1.2.2 Needles
1.2.3 Balloons
1.2.4 Cement Mixing and Delivery Devices
1.3 Vertebroplasty and Kyphoplasty Device Segment by Application
1.3.1 Global Vertebroplasty and Kyphoplasty Device Market Value by Application: (2024-2030)
1.3.2 Hospital
1.3.3 Ambulatory Surgery Center
1.3.4 Others
1.4 Global Vertebroplasty and Kyphoplasty Device Market Size Estimates and Forecasts
1.4.1 Global Vertebroplasty and Kyphoplasty Device Revenue 2019-2030
1.4.2 Global Vertebroplasty and Kyphoplasty Device Sales 2019-2030
1.4.3 Global Vertebroplasty and Kyphoplasty Device Market Average Price (2019-2030)
1.5 Assumptions and Limitations
2 Vertebroplasty and Kyphoplasty Device Market Competition by Manufacturers
2.1 Global Vertebroplasty and Kyphoplasty Device Sales Market Share by Manufacturers (2019-2024)
2.2 Global Vertebroplasty and Kyphoplasty Device Revenue Market Share by Manufacturers (2019-2024)
2.3 Global Vertebroplasty and Kyphoplasty Device Average Price by Manufacturers (2019-2024)
2.4 Global Vertebroplasty and Kyphoplasty Device Industry Ranking 2022 VS 2023 VS 2024
2.5 Global Key Manufacturers of Vertebroplasty and Kyphoplasty Device, Manufacturing Sites & Headquarters
2.6 Global Key Manufacturers of Vertebroplasty and Kyphoplasty Device, Product Type & Application
2.7 Vertebroplasty and Kyphoplasty Device Market Competitive Situation and Trends
2.7.1 Vertebroplasty and Kyphoplasty Device Market Concentration Rate
2.7.2 The Global Top 5 and Top 10 Largest Vertebroplasty and Kyphoplasty Device Players Market Share by Revenue
2.7.3 Global Vertebroplasty and Kyphoplasty Device Market Share by Company Type (Tier 1, Tier 2 and Tier 3)
2.8 Manufacturers Mergers & Acquisitions, Expansion Plans
3 Vertebroplasty and Kyphoplasty Device Retrospective Market Scenario by Region
3.1 Global Vertebroplasty and Kyphoplasty Device Market Size by Region: 2019 Versus 2023 Versus 2030
3.2 Global Vertebroplasty and Kyphoplasty Device Global Vertebroplasty and Kyphoplasty Device Sales by Region: 2019-2030
3.2.1 Global Vertebroplasty and Kyphoplasty Device Sales by Region: 2019-2024
3.2.2 Global Vertebroplasty and Kyphoplasty Device Sales by Region: 2025-2030
3.3 Global Vertebroplasty and Kyphoplasty Device Global Vertebroplasty and Kyphoplasty Device Revenue by Region: 2019-2030
3.3.1 Global Vertebroplasty and Kyphoplasty Device Revenue by Region: 2019-2024
3.3.2 Global Vertebroplasty and Kyphoplasty Device Revenue by Region: 2025-2030
3.4 North America Vertebroplasty and Kyphoplasty Device Market Facts & Figures by Country
3.4.1 North America Vertebroplasty and Kyphoplasty Device Market Size by Country: 2019 VS 2023 VS 2030
3.4.2 North America Vertebroplasty and Kyphoplasty Device Sales by Country (2019-2030)
3.4.3 North America Vertebroplasty and Kyphoplasty Device Revenue by Country (2019-2030)
3.4.4 U.S.
3.4.5 Canada
3.5 Europe Vertebroplasty and Kyphoplasty Device Market Facts & Figures by Country
3.5.1 Europe Vertebroplasty and Kyphoplasty Device Market Size by Country: 2019 VS 2023 VS 2030
3.5.2 Europe Vertebroplasty and Kyphoplasty Device Sales by Country (2019-2030)
3.5.3 Europe Vertebroplasty and Kyphoplasty Device Revenue by Country (2019-2030)
3.5.4 Germany
3.5.5 France
3.5.6 U.K.
3.5.7 Italy
3.5.8 Russia
3.6 Asia Pacific Vertebroplasty and Kyphoplasty Device Market Facts & Figures by Country
3.6.1 Asia Pacific Vertebroplasty and Kyphoplasty Device Market Size by Country: 2019 VS 2023 VS 2030
3.6.2 Asia Pacific Vertebroplasty and Kyphoplasty Device Sales by Country (2019-2030)
3.6.3 Asia Pacific Vertebroplasty and Kyphoplasty Device Revenue by Country (2019-2030)
3.6.4 China
3.6.5 Japan
3.6.6 South Korea
3.6.7 India
3.6.8 Australia
3.6.9 China Taiwan
3.6.10 Indonesia
3.6.11 Thailand
3.6.12 Malaysia
3.7 Latin America Vertebroplasty and Kyphoplasty Device Market Facts & Figures by Country
3.7.1 Latin America Vertebroplasty and Kyphoplasty Device Market Size by Country: 2019 VS 2023 VS 2030
3.7.2 Latin America Vertebroplasty and Kyphoplasty Device Sales by Country (2019-2030)
3.7.3 Latin America Vertebroplasty and Kyphoplasty Device Revenue by Country (2019-2030)
3.7.4 Mexico
3.7.5 Brazil
3.7.6 Argentina
3.8 Middle East and Africa Vertebroplasty and Kyphoplasty Device Market Facts & Figures by Country
3.8.1 Middle East and Africa Vertebroplasty and Kyphoplasty Device Market Size by Country: 2019 VS 2023 VS 2030
3.8.2 Middle East and Africa Vertebroplasty and Kyphoplasty Device Sales by Country (2019-2030)
3.8.3 Middle East and Africa Vertebroplasty and Kyphoplasty Device Revenue by Country (2019-2030)
3.8.4 Turkey
3.8.5 Saudi Arabia
3.8.6 UAE
4 Segment by Type
4.1 Global Vertebroplasty and Kyphoplasty Device Sales by Type (2019-2030)
4.1.1 Global Vertebroplasty and Kyphoplasty Device Sales by Type (2019-2024)
4.1.2 Global Vertebroplasty and Kyphoplasty Device Sales by Type (2025-2030)
4.1.3 Global Vertebroplasty and Kyphoplasty Device Sales Market Share by Type (2019-2030)
4.2 Global Vertebroplasty and Kyphoplasty Device Revenue by Type (2019-2030)
4.2.1 Global Vertebroplasty and Kyphoplasty Device Revenue by Type (2019-2024)
4.2.2 Global Vertebroplasty and Kyphoplasty Device Revenue by Type (2025-2030)
4.2.3 Global Vertebroplasty and Kyphoplasty Device Revenue Market Share by Type (2019-2030)
4.3 Global Vertebroplasty and Kyphoplasty Device Price by Type (2019-2030)
5 Segment by Application
5.1 Global Vertebroplasty and Kyphoplasty Device Sales by Application (2019-2030)
5.1.1 Global Vertebroplasty and Kyphoplasty Device Sales by Application (2019-2024)
5.1.2 Global Vertebroplasty and Kyphoplasty Device Sales by Application (2025-2030)
5.1.3 Global Vertebroplasty and Kyphoplasty Device Sales Market Share by Application (2019-2030)
5.2 Global Vertebroplasty and Kyphoplasty Device Revenue by Application (2019-2030)
5.2.1 Global Vertebroplasty and Kyphoplasty Device Revenue by Application (2019-2024)
5.2.2 Global Vertebroplasty and Kyphoplasty Device Revenue by Application (2025-2030)
5.2.3 Global Vertebroplasty and Kyphoplasty Device Revenue Market Share by Application (2019-2030)
5.3 Global Vertebroplasty and Kyphoplasty Device Price by Application (2019-2030)
6 Key Companies Profiled
6.1 Medtronic
6.1.1 Medtronic Corporation Information
6.1.2 Medtronic Description and Business Overview
6.1.3 Medtronic Vertebroplasty and Kyphoplasty Device Sales, Revenue and Gross Margin (2019-2024)
6.1.4 Medtronic Vertebroplasty and Kyphoplasty Device Product Portfolio
6.1.5 Medtronic Recent Developments/Updates
6.2 Stryker
6.2.1 Stryker Corporation Information
6.2.2 Stryker Description and Business Overview
6.2.3 Stryker Vertebroplasty and Kyphoplasty Device Sales, Revenue and Gross Margin (2019-2024)
6.2.4 Stryker Vertebroplasty and Kyphoplasty Device Product Portfolio
6.2.5 Stryker Recent Developments/Updates
6.3 DePuy Synthes (Johnson & Johnson)
6.3.1 DePuy Synthes (Johnson & Johnson) Corporation Information
6.3.2 DePuy Synthes (Johnson & Johnson) Description and Business Overview
6.3.3 DePuy Synthes (Johnson & Johnson) Vertebroplasty and Kyphoplasty Device Sales, Revenue and Gross Margin (2019-2024)
6.3.4 DePuy Synthes (Johnson & Johnson) Vertebroplasty and Kyphoplasty Device Product Portfolio
6.3.5 DePuy Synthes (Johnson & Johnson) Recent Developments/Updates
6.4 Globus Medical
6.4.1 Globus Medical Corporation Information
6.4.2 Globus Medical Description and Business Overview
6.4.3 Globus Medical Vertebroplasty and Kyphoplasty Device Sales, Revenue and Gross Margin (2019-2024)
6.4.4 Globus Medical Vertebroplasty and Kyphoplasty Device Product Portfolio
6.4.5 Globus Medical Recent Developments/Updates
6.5 Merit Medical Systems
6.5.1 Merit Medical Systems Corporation Information
6.5.2 Merit Medical Systems Description and Business Overview
6.5.3 Merit Medical Systems Vertebroplasty and Kyphoplasty Device Sales, Revenue and Gross Margin (2019-2024)
6.5.4 Merit Medical Systems Vertebroplasty and Kyphoplasty Device Product Portfolio
6.5.5 Merit Medical Systems Recent Developments/Updates
6.6 BMK Global Medical Company
6.6.1 BMK Global Medical Company Corporation Information
6.6.2 BMK Global Medical Company Description and Business Overview
6.6.3 BMK Global Medical Company Vertebroplasty and Kyphoplasty Device Sales, Revenue and Gross Margin (2019-2024)
6.6.4 BMK Global Medical Company Vertebroplasty and Kyphoplasty Device Product Portfolio
6.6.5 BMK Global Medical Company Recent Developments/Updates
6.7 IZI Medial Products
6.6.1 IZI Medial Products Corporation Information
6.6.2 IZI Medial Products Description and Business Overview
6.6.3 IZI Medial Products Vertebroplasty and Kyphoplasty Device Sales, Revenue and Gross Margin (2019-2024)
6.4.4 IZI Medial Products Vertebroplasty and Kyphoplasty Device Product Portfolio
6.7.5 IZI Medial Products Recent Developments/Updates
6.8 Zavation
6.8.1 Zavation Corporation Information
6.8.2 Zavation Description and Business Overview
6.8.3 Zavation Vertebroplasty and Kyphoplasty Device Sales, Revenue and Gross Margin (2019-2024)
6.8.4 Zavation Vertebroplasty and Kyphoplasty Device Product Portfolio
6.8.5 Zavation Recent Developments/Updates
6.9 G21 Srl
6.9.1 G21 Srl Corporation Information
6.9.2 G21 Srl Description and Business Overview
6.9.3 G21 Srl Vertebroplasty and Kyphoplasty Device Sales, Revenue and Gross Margin (2019-2024)
6.9.4 G21 Srl Vertebroplasty and Kyphoplasty Device Product Portfolio
6.9.5 G21 Srl Recent Developments/Updates
6.10 Joline
6.10.1 Joline Corporation Information
6.10.2 Joline Description and Business Overview
6.10.3 Joline Vertebroplasty and Kyphoplasty Device Sales, Revenue and Gross Margin (2019-2024)
6.10.4 Joline Vertebroplasty and Kyphoplasty Device Product Portfolio
6.10.5 Joline Recent Developments/Updates
6.11 Spine Wave
6.11.1 Spine Wave Corporation Information
6.11.2 Spine Wave Vertebroplasty and Kyphoplasty Device Description and Business Overview
6.11.3 Spine Wave Vertebroplasty and Kyphoplasty Device Sales, Revenue and Gross Margin (2019-2024)
6.11.4 Spine Wave Vertebroplasty and Kyphoplasty Device Product Portfolio
6.11.5 Spine Wave Recent Developments/Updates
6.12 Teknimed
6.12.1 Teknimed Corporation Information
6.12.2 Teknimed Vertebroplasty and Kyphoplasty Device Description and Business Overview
6.12.3 Teknimed Vertebroplasty and Kyphoplasty Device Sales, Revenue and Gross Margin (2019-2024)
6.12.4 Teknimed Vertebroplasty and Kyphoplasty Device Product Portfolio
6.12.5 Teknimed Recent Developments/Updates
6.13 PanMed
6.13.1 PanMed Corporation Information
6.13.2 PanMed Vertebroplasty and Kyphoplasty Device Description and Business Overview
6.13.3 PanMed Vertebroplasty and Kyphoplasty Device Sales, Revenue and Gross Margin (2019-2024)
6.13.4 PanMed Vertebroplasty and Kyphoplasty Device Product Portfolio
6.13.5 PanMed Recent Developments/Updates
6.14 Biopsybell
6.14.1 Biopsybell Corporation Information
6.14.2 Biopsybell Vertebroplasty and Kyphoplasty Device Description and Business Overview
6.14.3 Biopsybell Vertebroplasty and Kyphoplasty Device Sales, Revenue and Gross Margin (2019-2024)
6.14.4 Biopsybell Vertebroplasty and Kyphoplasty Device Product Portfolio
6.14.5 Biopsybell Recent Developments/Updates
7 Industry Chain and Sales Channels Analysis
7.1 Vertebroplasty and Kyphoplasty Device Industry Chain Analysis
7.2 Vertebroplasty and Kyphoplasty Device Key Raw Materials
7.2.1 Key Raw Materials
7.2.2 Raw Materials Key Suppliers
7.3 Vertebroplasty and Kyphoplasty Device Production Mode & Process
7.4 Vertebroplasty and Kyphoplasty Device Sales and Marketing
7.4.1 Vertebroplasty and Kyphoplasty Device Sales Channels
7.4.2 Vertebroplasty and Kyphoplasty Device Distributors
7.5 Vertebroplasty and Kyphoplasty Device Customers
8 Vertebroplasty and Kyphoplasty Device Market Dynamics
8.1 Vertebroplasty and Kyphoplasty Device Industry Trends
8.2 Vertebroplasty and Kyphoplasty Device Market Drivers
8.3 Vertebroplasty and Kyphoplasty Device Market Challenges
8.4 Vertebroplasty and Kyphoplasty Device Market Restraints
9 Research Finding and Conclusion
10 Methodology and Data Source
10.1 Methodology/Research Approach
10.1.1 Research Programs/Design
10.1.2 Market Size Estimation
10.1.3 Market Breakdown and Data Triangulation
10.2 Data Source
10.2.1 Secondary Sources
10.2.2 Primary Sources
10.3 Author List
10.4 Disclaimer
Published By : QY Research
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