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Inhaled Nitric Oxide-Global Market Insights and Sales Trends 2025
Synopsis
Nitric oxide is a chemical compound in gas form that is sometimes used to treat infants with severe breathing problems associated with narrow blood vessels in the lungs. It works by relaxing smooth muscle to widen (dilate) blood vessels, especially in the lungs. Nitric oxide is usually used together with a breathing machine (ventilator).
Inhaled nitric oxide (iNO) is recognized as a potent and selective pulmonary vasodilator that does not decrease systemic vascular tone. The therapeutic application of iNO in human was first described in 1990s. INO therapy was effective to improve oxygenation in infants with persistent pulmonary hypertension of the newborn (PPHN). Owing to its selective pulmonary vasodilator effects, iNO therapy is an important treatment for term newborns with hypoxemic respiratory failure due to PPHN. The Food and Drug Administration of the United States of America first approved iNO in 1999 for use as a medical gas to treat hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension in term and late preterm neonates. Thereafter, iNO therapy is clinically applied to treat PPHN in term and late preterm neonates without consensus.
The global Inhaled Nitric Oxide market size is expected to reach US$ 1906.6 million by 2029, growing at a CAGR of 8.3% from 2023 to 2029. The market is mainly driven by the significant applications of Inhaled Nitric Oxide in various end use industries. The expanding demands from the Near-term and Pre-term Infants PPHN, Children and Adult ARDS and Other Diseases,, are propelling Inhaled Nitric Oxide market. 800 ppm, one of the segments analysed in this report, is projected to record % CAGR and reach US$ million by the end of the analysis period. Growth in the 100 ppm segment is estimated at % CAGR for the next seven-year period.
Mallinckrodt monopolizes the global Inhaled Nitric Oxide market, holding a share about 65%.
North America is the largest market, with a share about 77%, followed by Asia-Pacific and Europe, have a share about 20 percent.
In terms of product, 800 ppm is the largest segment, with a share over 50%. And in terms of application, the largest application is Near-term and Pre-term Infants PPHN, followed by Children and Adult ARDS, etc.
Report Objectives
This report provides market insight on the different segments, by manufacturers, by Type, by Application. Market size and forecast (2018-2029) has been provided in the report. The primary objectives of this report are to provide 1) global market size and forecasts, growth rates, market dynamics, industry structure and developments, market situation, trends; 2) global market share and ranking by company; 3) comprehensive presentation of the global market for Inhaled Nitric Oxide, with both quantitative and qualitative analysis through detailed segmentation; 4) detailed value chain analysis and review of growth factors essential for the existing market players and new entrants; 5) emerging opportunities in the market and the future impact of major drivers and restraints of the market.
Key Features of The Study:
This report provides in-depth analysis of the global Inhaled Nitric Oxide market, and provides market size (US$ million) and CAGR for the forecast period (2023-2029), considering 2022 as the base year.
This report profiles key players in the global Inhaled Nitric Oxide market based on the following parameters - company details (found date, headquarters, manufacturing bases), products portfolio, Inhaled Nitric Oxide sales data, market share and ranking.
This report elucidates potential market opportunities across different segments and explains attractive investment proposition matrices for this market.
This report illustrates key insights about market drivers, restraints, opportunities, market trends, regional outlook.
Key companies of Inhaled Nitric Oxide covered in this report include Mallinckrodt, Praxair (Linde plc), Air Liquide and BOC Healthcare (Linde Group), etc.
The global Inhaled Nitric Oxide market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts.
Market Segmentation
Company Profiles:
Mallinckrodt
Praxair (Linde plc)
Air Liquide
BOC Healthcare (Linde Group)
Global Inhaled Nitric Oxide market, by region:
North America (U.S., Canada, Mexico)
Europe (Germany, France, UK, Italy, etc.)
Asia Pacific (China, Japan, South Korea, Southeast Asia, India, etc.)
South America (Brazil, etc.)
Middle East and Africa (Turkey, GCC Countries, Africa, etc.)
Global Inhaled Nitric Oxide market, Segment by Type:
800 ppm
100 ppm
Others
Global Inhaled Nitric Oxide market, by Application
Near-term and Pre-term Infants PPHN
Children and Adult ARDS
Other Diseases
Core Chapters
Chapter One: Introduces the study scope of this report, executive summary of market segments by Type, market size segments for North America, Europe, Asia Pacific, South America, Middle East & Africa.
Chapter Two: Detailed analysis of Inhaled Nitric Oxide manufacturers competitive landscape, price, sales, revenue, market share and ranking, latest development plan, merger, and acquisition information, etc.
Chapter Three: Sales, revenue of Inhaled Nitric Oxide in regional level. It provides a quantitative analysis of the market size and development potential of each region and introduces the future development prospects, and market space in the world.
Chapter Four: Introduces market segments by Application, market size segment for North America, Europe, Asia Pacific, South America, Middle East & Africa.
Chapter Five, Six, Seven, Eight and Nine: North America, Europe, Asia Pacific, South America, Middle East & Africa, sales and revenue by country.
Chapter Ten: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter Eleven: Analysis of industrial chain, key raw materials, manufacturing cost, and market dynamics. Introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter Twelve: Analysis of sales channel, distributors and customers.
Chapter Thirteen: Research Findings and Conclusion.
Nitric oxide is a chemical compound in gas form that is sometimes used to treat infants with severe breathing problems associated with narrow blood vessels in the lungs. It works by relaxing smooth muscle to widen (dilate) blood vessels, especially in the lungs. Nitric oxide is usually used together with a breathing machine (ventilator).
Inhaled nitric oxide (iNO) is recognized as a potent and selective pulmonary vasodilator that does not decrease systemic vascular tone. The therapeutic application of iNO in human was first described in 1990s. INO therapy was effective to improve oxygenation in infants with persistent pulmonary hypertension of the newborn (PPHN). Owing to its selective pulmonary vasodilator effects, iNO therapy is an important treatment for term newborns with hypoxemic respiratory failure due to PPHN. The Food and Drug Administration of the United States of America first approved iNO in 1999 for use as a medical gas to treat hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension in term and late preterm neonates. Thereafter, iNO therapy is clinically applied to treat PPHN in term and late preterm neonates without consensus.
The global Inhaled Nitric Oxide market size is expected to reach US$ 1906.6 million by 2029, growing at a CAGR of 8.3% from 2023 to 2029. The market is mainly driven by the significant applications of Inhaled Nitric Oxide in various end use industries. The expanding demands from the Near-term and Pre-term Infants PPHN, Children and Adult ARDS and Other Diseases,, are propelling Inhaled Nitric Oxide market. 800 ppm, one of the segments analysed in this report, is projected to record % CAGR and reach US$ million by the end of the analysis period. Growth in the 100 ppm segment is estimated at % CAGR for the next seven-year period.
Mallinckrodt monopolizes the global Inhaled Nitric Oxide market, holding a share about 65%.
North America is the largest market, with a share about 77%, followed by Asia-Pacific and Europe, have a share about 20 percent.
In terms of product, 800 ppm is the largest segment, with a share over 50%. And in terms of application, the largest application is Near-term and Pre-term Infants PPHN, followed by Children and Adult ARDS, etc.
Report Objectives
This report provides market insight on the different segments, by manufacturers, by Type, by Application. Market size and forecast (2018-2029) has been provided in the report. The primary objectives of this report are to provide 1) global market size and forecasts, growth rates, market dynamics, industry structure and developments, market situation, trends; 2) global market share and ranking by company; 3) comprehensive presentation of the global market for Inhaled Nitric Oxide, with both quantitative and qualitative analysis through detailed segmentation; 4) detailed value chain analysis and review of growth factors essential for the existing market players and new entrants; 5) emerging opportunities in the market and the future impact of major drivers and restraints of the market.
Key Features of The Study:
This report provides in-depth analysis of the global Inhaled Nitric Oxide market, and provides market size (US$ million) and CAGR for the forecast period (2023-2029), considering 2022 as the base year.
This report profiles key players in the global Inhaled Nitric Oxide market based on the following parameters - company details (found date, headquarters, manufacturing bases), products portfolio, Inhaled Nitric Oxide sales data, market share and ranking.
This report elucidates potential market opportunities across different segments and explains attractive investment proposition matrices for this market.
This report illustrates key insights about market drivers, restraints, opportunities, market trends, regional outlook.
Key companies of Inhaled Nitric Oxide covered in this report include Mallinckrodt, Praxair (Linde plc), Air Liquide and BOC Healthcare (Linde Group), etc.
The global Inhaled Nitric Oxide market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts.
Market Segmentation
Company Profiles:
Mallinckrodt
Praxair (Linde plc)
Air Liquide
BOC Healthcare (Linde Group)
Global Inhaled Nitric Oxide market, by region:
North America (U.S., Canada, Mexico)
Europe (Germany, France, UK, Italy, etc.)
Asia Pacific (China, Japan, South Korea, Southeast Asia, India, etc.)
South America (Brazil, etc.)
Middle East and Africa (Turkey, GCC Countries, Africa, etc.)
Global Inhaled Nitric Oxide market, Segment by Type:
800 ppm
100 ppm
Others
Global Inhaled Nitric Oxide market, by Application
Near-term and Pre-term Infants PPHN
Children and Adult ARDS
Other Diseases
Core Chapters
Chapter One: Introduces the study scope of this report, executive summary of market segments by Type, market size segments for North America, Europe, Asia Pacific, South America, Middle East & Africa.
Chapter Two: Detailed analysis of Inhaled Nitric Oxide manufacturers competitive landscape, price, sales, revenue, market share and ranking, latest development plan, merger, and acquisition information, etc.
Chapter Three: Sales, revenue of Inhaled Nitric Oxide in regional level. It provides a quantitative analysis of the market size and development potential of each region and introduces the future development prospects, and market space in the world.
Chapter Four: Introduces market segments by Application, market size segment for North America, Europe, Asia Pacific, South America, Middle East & Africa.
Chapter Five, Six, Seven, Eight and Nine: North America, Europe, Asia Pacific, South America, Middle East & Africa, sales and revenue by country.
Chapter Ten: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter Eleven: Analysis of industrial chain, key raw materials, manufacturing cost, and market dynamics. Introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter Twelve: Analysis of sales channel, distributors and customers.
Chapter Thirteen: Research Findings and Conclusion.
Index1 Inhaled Nitric Oxide Market Overview
1.1 Inhaled Nitric Oxide Product Overview
1.2 Inhaled Nitric Oxide Market Segment by Type
1.2.1 800 ppm
1.2.2 100 ppm
1.2.3 Others
1.3 Global Inhaled Nitric Oxide Market Size by Type
1.3.1 Global Inhaled Nitric Oxide Market Size Overview by Type (2018-2029)
1.3.2 Global Inhaled Nitric Oxide Historic Market Size Review by Type (2018-2023)
1.3.3 Global Inhaled Nitric Oxide Forecasted Market Size by Type (2024-2029)
1.4 Key Regions Market Size Segment by Type
1.4.1 North America Inhaled Nitric Oxide Sales Breakdown by Type (2018-2023)
1.4.2 Europe Inhaled Nitric Oxide Sales Breakdown by Type (2018-2023)
1.4.3 Asia-Pacific Inhaled Nitric Oxide Sales Breakdown by Type (2018-2023)
1.4.4 Latin America Inhaled Nitric Oxide Sales Breakdown by Type (2018-2023)
1.4.5 Middle East and Africa Inhaled Nitric Oxide Sales Breakdown by Type (2018-2023)
2 Global Inhaled Nitric Oxide Market Competition by Company
2.1 Global Top Players by Inhaled Nitric Oxide Sales (2018-2023)
2.2 Global Top Players by Inhaled Nitric Oxide Revenue (2018-2023)
2.3 Global Top Players by Inhaled Nitric Oxide Price (2018-2023)
2.4 Global Top Manufacturers Inhaled Nitric Oxide Manufacturing Base Distribution, Sales Area, Product Type
2.5 Inhaled Nitric Oxide Market Competitive Situation and Trends
2.5.1 Inhaled Nitric Oxide Market Concentration Rate (2018-2023)
2.5.2 Global 5 and 10 Largest Manufacturers by Inhaled Nitric Oxide Sales and Revenue in 2022
2.6 Global Top Manufacturers by Company Type (Tier 1, Tier 2 and Tier 3) & (based on the Revenue in Inhaled Nitric Oxide as of 2022)
2.7 Date of Key Manufacturers Enter into Inhaled Nitric Oxide Market
2.8 Key Manufacturers Inhaled Nitric Oxide Product Offered
2.9 Mergers & Acquisitions, Expansion
3 Inhaled Nitric Oxide Status and Outlook by Region
3.1 Global Inhaled Nitric Oxide Market Size and CAGR by Region: 2018 VS 2022 VS 2029
3.2 Global Inhaled Nitric Oxide Historic Market Size by Region
3.2.1 Global Inhaled Nitric Oxide Sales in Volume by Region (2018-2023)
3.2.2 Global Inhaled Nitric Oxide Sales in Value by Region (2018-2023)
3.2.3 Global Inhaled Nitric Oxide Sales (Volume & Value) Price and Gross Margin (2018-2023)
3.3 Global Inhaled Nitric Oxide Forecasted Market Size by Region
3.3.1 Global Inhaled Nitric Oxide Sales in Volume by Region (2024-2029)
3.3.2 Global Inhaled Nitric Oxide Sales in Value by Region (2024-2029)
3.3.3 Global Inhaled Nitric Oxide Sales (Volume & Value), Price and Gross Margin (2024-2029)
4 Global Inhaled Nitric Oxide by Application
4.1 Inhaled Nitric Oxide Market Segment by Application
4.1.1 Near-term and Pre-term Infants PPHN
4.1.2 Children and Adult ARDS
4.1.3 Other Diseases
4.2 Global Inhaled Nitric Oxide Market Size by Application
4.2.1 Global Inhaled Nitric Oxide Market Size Overview by Application (2018-2029)
4.2.2 Global Inhaled Nitric Oxide Historic Market Size Review by Application (2018-2023)
4.2.3 Global Inhaled Nitric Oxide Forecasted Market Size by Application (2024-2029)
4.3 Key Regions Market Size Segment by Application
4.3.1 North America Inhaled Nitric Oxide Sales Breakdown by Application (2018-2023)
4.3.2 Europe Inhaled Nitric Oxide Sales Breakdown by Application (2018-2023)
4.3.3 Asia-Pacific Inhaled Nitric Oxide Sales Breakdown by Application (2018-2023)
4.3.4 Latin America Inhaled Nitric Oxide Sales Breakdown by Application (2018-2023)
4.3.5 Middle East and Africa Inhaled Nitric Oxide Sales Breakdown by Application (2018-2023)
5 North America Inhaled Nitric Oxide by Country
5.1 North America Inhaled Nitric Oxide Historic Market Size by Country
5.1.1 North America Inhaled Nitric Oxide Market Size Growth Rate (CAGR) by Country: 2018 VS 2022 VS 2029
5.1.2 North America Inhaled Nitric Oxide Sales in Volume by Country (2018-2023)
5.1.3 North America Inhaled Nitric Oxide Sales in Value by Country (2018-2023)
5.2 North America Inhaled Nitric Oxide Forecasted Market Size by Country
5.2.1 North America Inhaled Nitric Oxide Sales in Volume by Country (2024-2029)
5.2.2 North America Inhaled Nitric Oxide Sales in Value by Country (2024-2029)
6 Europe Inhaled Nitric Oxide by Country
6.1 Europe Inhaled Nitric Oxide Historic Market Size by Country
6.1.1 Europe Inhaled Nitric Oxide Market Size Growth Rate (CAGR) by Country: 2018 VS 2022 VS 2029
6.1.2 Europe Inhaled Nitric Oxide Sales in Volume by Country (2018-2023)
6.1.3 Europe Inhaled Nitric Oxide Sales in Value by Country (2018-2023)
6.2 Europe Inhaled Nitric Oxide Forecasted Market Size by Country
6.2.1 Europe Inhaled Nitric Oxide Sales in Volume by Country (2024-2029)
6.2.2 Europe Inhaled Nitric Oxide Sales in Value by Country (2024-2029)
7 Asia-Pacific Inhaled Nitric Oxide by Region
7.1 Asia-Pacific Inhaled Nitric Oxide Historic Market Size by Region
7.1.1 Asia-Pacific Inhaled Nitric Oxide Market Size Growth Rate (CAGR) by Region: 2018 VS 2022 VS 2029
7.1.2 Asia-Pacific Inhaled Nitric Oxide Sales in Volume by Region (2018-2023)
7.1.3 Asia-Pacific Inhaled Nitric Oxide Sales in Value by Region (2018-2023)
7.2 Asia-Pacific Inhaled Nitric Oxide Forecasted Market Size by Region
7.2.1 Asia-Pacific Inhaled Nitric Oxide Sales in Volume by Region (2024-2029)
7.2.2 Asia-Pacific Inhaled Nitric Oxide Sales in Value by Region (2024-2029)
8 Latin America Inhaled Nitric Oxide by Country
8.1 Latin America Inhaled Nitric Oxide Historic Market Size by Country
8.1.1 Latin America Inhaled Nitric Oxide Market Size Growth Rate (CAGR) by Country: 2018 VS 2022 VS 2029
8.1.2 Latin America Inhaled Nitric Oxide Sales in Volume by Country (2018-2023)
8.1.3 Latin America Inhaled Nitric Oxide Sales in Value by Country (2018-2023)
8.2 Latin America Inhaled Nitric Oxide Forecasted Market Size by Country
8.2.1 Latin America Inhaled Nitric Oxide Sales in Volume by Country (2024-2029)
8.2.2 Latin America Inhaled Nitric Oxide Sales in Value by Country (2024-2029)
9 Middle East and Africa Inhaled Nitric Oxide by Country
9.1 Middle East and Africa Inhaled Nitric Oxide Historic Market Size by Country
9.1.1 Middle East and Africa Inhaled Nitric Oxide Market Size Growth Rate (CAGR) by Country: 2018 VS 2022 VS 2029
9.1.2 Middle East and Africa Inhaled Nitric Oxide Sales in Volume by Country (2018-2023)
9.1.3 Middle East and Africa Inhaled Nitric Oxide Sales in Value by Country (2018-2023)
9.2 Middle East and Africa Inhaled Nitric Oxide Forecasted Market Size by Country
9.2.1 Middle East and Africa Inhaled Nitric Oxide Sales in Volume by Country (2024-2029)
9.2.2 Middle East and Africa Inhaled Nitric Oxide Sales in Value by Country (2024-2029)
10 Company Profiles
10.1 Mallinckrodt
10.1.1 Mallinckrodt Company Information
10.1.2 Mallinckrodt Introduction and Business Overview
10.1.3 Mallinckrodt Inhaled Nitric Oxide Sales, Revenue and Gross Margin (2018-2023)
10.1.4 Mallinckrodt Inhaled Nitric Oxide Products Offered
10.1.5 Mallinckrodt Recent Development
10.2 Praxair (Linde plc)
10.2.1 Praxair (Linde plc) Company Information
10.2.2 Praxair (Linde plc) Introduction and Business Overview
10.2.3 Praxair (Linde plc) Inhaled Nitric Oxide Sales, Revenue and Gross Margin (2018-2023)
10.2.4 Praxair (Linde plc) Inhaled Nitric Oxide Products Offered
10.2.5 Praxair (Linde plc) Recent Development
10.3 Air Liquide
10.3.1 Air Liquide Company Information
10.3.2 Air Liquide Introduction and Business Overview
10.3.3 Air Liquide Inhaled Nitric Oxide Sales, Revenue and Gross Margin (2018-2023)
10.3.4 Air Liquide Inhaled Nitric Oxide Products Offered
10.3.5 Air Liquide Recent Development
10.4 BOC Healthcare (Linde Group)
10.4.1 BOC Healthcare (Linde Group) Company Information
10.4.2 BOC Healthcare (Linde Group) Introduction and Business Overview
10.4.3 BOC Healthcare (Linde Group) Inhaled Nitric Oxide Sales, Revenue and Gross Margin (2018-2023)
10.4.4 BOC Healthcare (Linde Group) Inhaled Nitric Oxide Products Offered
10.4.5 BOC Healthcare (Linde Group) Recent Development
11 Upstream, Opportunities, Challenges, Risks and Influences Factors Analysis
11.1 Inhaled Nitric Oxide Key Raw Materials
11.1.1 Key Raw Materials
11.1.2 Key Raw Materials Price
11.1.3 Raw Materials Key Suppliers
11.2 Manufacturing Cost Structure
11.2.1 Raw Materials
11.2.2 Labor Cost
11.2.3 Manufacturing Expenses
11.3 Inhaled Nitric Oxide Industrial Chain Analysis
11.4 Inhaled Nitric Oxide Market Dynamics
11.4.1 Inhaled Nitric Oxide Industry Trends
11.4.2 Inhaled Nitric Oxide Market Drivers
11.4.3 Inhaled Nitric Oxide Market Challenges
11.4.4 Inhaled Nitric Oxide Market Restraints
12 Market Strategy Analysis, Distributors
12.1 Sales Channel
12.2 Inhaled Nitric Oxide Distributors
12.3 Inhaled Nitric Oxide Downstream Customers
13 Research Findings and Conclusion
14 Appendix
14.1 Research Methodology
14.1.1 Methodology/Research Approach
14.1.2 Data Source
14.2 Author Details
14.3 Disclaimer
Published By : QY Research
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