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Protein A Chromatography Resin-Global Market Insights and Sales Trends 2025

Protein A Chromatography Resin-Global Market Insights and Sales Trends 2025

Publishing Date : Mar, 2025

License Type :
 

Report Code : 1818785

No of Pages : 90

Synopsis
Protein A chromatography resin is a specialized medium used in protein purification processes based on the affinity chromatography technique. It is designed to selectively bind and purify antibodies and antibody-based molecules, such as monoclonal antibodies (mAbs), from complex mixtures like cell culture supernatants or biopharmaceutical production streams. Protein A is a bacterial protein derived from Staphylococcus aureus, and it exhibits a strong affinity for the Fc region of immunoglobulin G (IgG) antibodies.
The resin consists of porous beads to which Protein A molecules are immobilized. When a mixture containing antibodies is passed through the column containing the Protein A chromatography resin, the antibodies specifically bind to the Protein A ligands while other unwanted impurities flow through the column. The bound antibodies are then eluted from the resin using a buffer or elution solution, resulting in highly purified antibodies suitable for therapeutic or research applications.

The global Protein A Chromatography Resin market size is expected to reach US$ 155.5 million by 2029, growing at a CAGR of 6.1% from 2023 to 2029. The market is mainly driven by the significant applications of Protein A Chromatography Resin in various end use industries. The expanding demands from the Research and Pharmaceuticals, are propelling Protein A Chromatography Resin market. Monoclonal Antibodies, one of the segments analysed in this report, is projected to record % CAGR and reach US$ million by the end of the analysis period. Growth in the Non-antibody Protein segment is estimated at % CAGR for the next seven-year period.
The market for protein A chromatography resin is a critical component of the biopharmaceutical industry. The increasing demand for monoclonal antibodies and antibody-based therapeutics has driven the growth of this market. Some key factors influencing the protein A chromatography resin market include:
Biopharmaceutical Industry Growth: The biopharmaceutical industry's expansion, driven by the development and approval of new monoclonal antibody-based drugs, has significantly boosted the demand for protein A chromatography resins.
Monoclonal Antibody Therapeutics: Monoclonal antibodies (mAbs) have become essential tools in treating various diseases, including cancer, autoimmune disorders, and infectious diseases. Protein A chromatography resins play a vital role in the purification of these antibodies during the bioprocessing stage.
Quality and Purity Requirements: The biopharmaceutical industry places a strong emphasis on product quality and purity. Protein A chromatography resin offers a highly selective and efficient method for achieving the required purity levels in the purification of antibodies.
Increasing Demand for Biologics: Biologics, including monoclonal antibodies, are gaining prominence in healthcare due to their high specificity and therapeutic efficacy. The production of biologics necessitates efficient purification methods like Protein A chromatography.
Advancements in Bioprocessing Technology: Ongoing advancements in bioprocessing technology have led to the development of improved Protein A chromatography resins with enhanced performance and increased capacity.
Biosimilars Development: The development of biosimilars, which are similar versions of approved biologic drugs, also drives the demand for Protein A chromatography resin as these biosimilars require efficient purification processes.
Increasing Research in Immunotherapy: The growing focus on immunotherapy and the development of personalized medicine have spurred research into novel antibodies, leading to a greater need for efficient antibody purification methods.
The protein A chromatography resin market is expected to continue growing as the demand for monoclonal antibodies and antibody-based therapeutics remains strong. Manufacturers of biopharmaceuticals and contract manufacturing organizations (CMOs) are likely to invest in efficient and reliable purification technologies like Protein A chromatography resins to meet the increasing demand for high-quality therapeutic antibodies. Additionally, ongoing research and development efforts may lead to the introduction of improved and innovative chromatography resins, further driving the growth of this market.

Report Objectives
This report provides market insight on the different segments, by manufacturers, by Type, by Application. Market size and forecast (2018-2029) has been provided in the report. The primary objectives of this report are to provide 1) global market size and forecasts, growth rates, market dynamics, industry structure and developments, market situation, trends; 2) global market share and ranking by company; 3) comprehensive presentation of the global market for Protein A Chromatography Resin, with both quantitative and qualitative analysis through detailed segmentation; 4) detailed value chain analysis and review of growth factors essential for the existing market players and new entrants; 5) emerging opportunities in the market and the future impact of major drivers and restraints of the market.
Key Features of The Study:
This report provides in-depth analysis of the global Protein A Chromatography Resin market, and provides market size (US$ million) and CAGR for the forecast period (2023-2029), considering 2022 as the base year.
This report profiles key players in the global Protein A Chromatography Resin market based on the following parameters - company details (found date, headquarters, manufacturing bases), products portfolio, Protein A Chromatography Resin sales data, market share and ranking.
This report elucidates potential market opportunities across different segments and explains attractive investment proposition matrices for this market.
This report illustrates key insights about market drivers, restraints, opportunities, market trends, regional outlook.
Key companies of Protein A Chromatography Resin covered in this report include Merck KGaA, Tosoh Bioscience, GE Healthcare, Bio-Rad Laboratories and Thermo Fisher Scientific, etc.
The global Protein A Chromatography Resin market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts.
Market Segmentation
Company Profiles:
Merck KGaA
Tosoh Bioscience
GE Healthcare
Bio-Rad Laboratories
Thermo Fisher Scientific
Global Protein A Chromatography Resin market, by region:
North America (U.S., Canada, Mexico)
Europe (Germany, France, UK, Italy, etc.)
Asia Pacific (China, Japan, South Korea, Southeast Asia, India, etc.)
South America (Brazil, etc.)
Middle East and Africa (Turkey, GCC Countries, Africa, etc.)
Global Protein A Chromatography Resin market, Segment by Type:
Monoclonal Antibodies
Non-antibody Protein
Polyclonal Antibodies
Others
Global Protein A Chromatography Resin market, by Application
Research
Pharmaceuticals
Core Chapters
Chapter One: Introduces the study scope of this report, executive summary of market segments by Type, market size segments for North America, Europe, Asia Pacific, South America, Middle East & Africa.
Chapter Two: Detailed analysis of Protein A Chromatography Resin manufacturers competitive landscape, price, sales, revenue, market share and ranking, latest development plan, merger, and acquisition information, etc.
Chapter Three: Sales, revenue of Protein A Chromatography Resin in regional level. It provides a quantitative analysis of the market size and development potential of each region and introduces the future development prospects, and market space in the world.
Chapter Four: Introduces market segments by Application, market size segment for North America, Europe, Asia Pacific, South America, Middle East & Africa.
Chapter Five, Six, Seven, Eight and Nine: North America, Europe, Asia Pacific, South America, Middle East & Africa, sales and revenue by country.
Chapter Ten: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter Eleven: Analysis of industrial chain, key raw materials, manufacturing cost, and market dynamics. Introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter Twelve: Analysis of sales channel, distributors and customers.
Chapter Thirteen: Research Findings and Conclusion.
Index
1 Protein A Chromatography Resin Market Overview
1.1 Protein A Chromatography Resin Product Overview
1.2 Protein A Chromatography Resin Market Segment by Type
1.2.1 Monoclonal Antibodies
1.2.2 Non-antibody Protein
1.2.3 Polyclonal Antibodies
1.2.4 Others
1.3 Global Protein A Chromatography Resin Market Size by Type
1.3.1 Global Protein A Chromatography Resin Market Size Overview by Type (2018-2029)
1.3.2 Global Protein A Chromatography Resin Historic Market Size Review by Type (2018-2023)
1.3.3 Global Protein A Chromatography Resin Forecasted Market Size by Type (2024-2029)
1.4 Key Regions Market Size Segment by Type
1.4.1 North America Protein A Chromatography Resin Sales Breakdown by Type (2018-2023)
1.4.2 Europe Protein A Chromatography Resin Sales Breakdown by Type (2018-2023)
1.4.3 Asia-Pacific Protein A Chromatography Resin Sales Breakdown by Type (2018-2023)
1.4.4 Latin America Protein A Chromatography Resin Sales Breakdown by Type (2018-2023)
1.4.5 Middle East and Africa Protein A Chromatography Resin Sales Breakdown by Type (2018-2023)
2 Global Protein A Chromatography Resin Market Competition by Company
2.1 Global Top Players by Protein A Chromatography Resin Sales (2018-2023)
2.2 Global Top Players by Protein A Chromatography Resin Revenue (2018-2023)
2.3 Global Top Players by Protein A Chromatography Resin Price (2018-2023)
2.4 Global Top Manufacturers Protein A Chromatography Resin Manufacturing Base Distribution, Sales Area, Product Type
2.5 Protein A Chromatography Resin Market Competitive Situation and Trends
2.5.1 Protein A Chromatography Resin Market Concentration Rate (2018-2023)
2.5.2 Global 5 and 10 Largest Manufacturers by Protein A Chromatography Resin Sales and Revenue in 2022
2.6 Global Top Manufacturers by Company Type (Tier 1, Tier 2 and Tier 3) & (based on the Revenue in Protein A Chromatography Resin as of 2022)
2.7 Date of Key Manufacturers Enter into Protein A Chromatography Resin Market
2.8 Key Manufacturers Protein A Chromatography Resin Product Offered
2.9 Mergers & Acquisitions, Expansion
3 Protein A Chromatography Resin Status and Outlook by Region
3.1 Global Protein A Chromatography Resin Market Size and CAGR by Region: 2018 VS 2022 VS 2029
3.2 Global Protein A Chromatography Resin Historic Market Size by Region
3.2.1 Global Protein A Chromatography Resin Sales in Volume by Region (2018-2023)
3.2.2 Global Protein A Chromatography Resin Sales in Value by Region (2018-2023)
3.2.3 Global Protein A Chromatography Resin Sales (Volume & Value) Price and Gross Margin (2018-2023)
3.3 Global Protein A Chromatography Resin Forecasted Market Size by Region
3.3.1 Global Protein A Chromatography Resin Sales in Volume by Region (2024-2029)
3.3.2 Global Protein A Chromatography Resin Sales in Value by Region (2024-2029)
3.3.3 Global Protein A Chromatography Resin Sales (Volume & Value), Price and Gross Margin (2024-2029)
4 Global Protein A Chromatography Resin by Application
4.1 Protein A Chromatography Resin Market Segment by Application
4.1.1 Research
4.1.2 Pharmaceuticals
4.2 Global Protein A Chromatography Resin Market Size by Application
4.2.1 Global Protein A Chromatography Resin Market Size Overview by Application (2018-2029)
4.2.2 Global Protein A Chromatography Resin Historic Market Size Review by Application (2018-2023)
4.2.3 Global Protein A Chromatography Resin Forecasted Market Size by Application (2024-2029)
4.3 Key Regions Market Size Segment by Application
4.3.1 North America Protein A Chromatography Resin Sales Breakdown by Application (2018-2023)
4.3.2 Europe Protein A Chromatography Resin Sales Breakdown by Application (2018-2023)
4.3.3 Asia-Pacific Protein A Chromatography Resin Sales Breakdown by Application (2018-2023)
4.3.4 Latin America Protein A Chromatography Resin Sales Breakdown by Application (2018-2023)
4.3.5 Middle East and Africa Protein A Chromatography Resin Sales Breakdown by Application (2018-2023)
5 North America Protein A Chromatography Resin by Country
5.1 North America Protein A Chromatography Resin Historic Market Size by Country
5.1.1 North America Protein A Chromatography Resin Market Size Growth Rate (CAGR) by Country: 2018 VS 2022 VS 2029
5.1.2 North America Protein A Chromatography Resin Sales in Volume by Country (2018-2023)
5.1.3 North America Protein A Chromatography Resin Sales in Value by Country (2018-2023)
5.2 North America Protein A Chromatography Resin Forecasted Market Size by Country
5.2.1 North America Protein A Chromatography Resin Sales in Volume by Country (2024-2029)
5.2.2 North America Protein A Chromatography Resin Sales in Value by Country (2024-2029)
6 Europe Protein A Chromatography Resin by Country
6.1 Europe Protein A Chromatography Resin Historic Market Size by Country
6.1.1 Europe Protein A Chromatography Resin Market Size Growth Rate (CAGR) by Country: 2018 VS 2022 VS 2029
6.1.2 Europe Protein A Chromatography Resin Sales in Volume by Country (2018-2023)
6.1.3 Europe Protein A Chromatography Resin Sales in Value by Country (2018-2023)
6.2 Europe Protein A Chromatography Resin Forecasted Market Size by Country
6.2.1 Europe Protein A Chromatography Resin Sales in Volume by Country (2024-2029)
6.2.2 Europe Protein A Chromatography Resin Sales in Value by Country (2024-2029)
7 Asia-Pacific Protein A Chromatography Resin by Region
7.1 Asia-Pacific Protein A Chromatography Resin Historic Market Size by Region
7.1.1 Asia-Pacific Protein A Chromatography Resin Market Size Growth Rate (CAGR) by Region: 2018 VS 2022 VS 2029
7.1.2 Asia-Pacific Protein A Chromatography Resin Sales in Volume by Region (2018-2023)
7.1.3 Asia-Pacific Protein A Chromatography Resin Sales in Value by Region (2018-2023)
7.2 Asia-Pacific Protein A Chromatography Resin Forecasted Market Size by Region
7.2.1 Asia-Pacific Protein A Chromatography Resin Sales in Volume by Region (2024-2029)
7.2.2 Asia-Pacific Protein A Chromatography Resin Sales in Value by Region (2024-2029)
8 Latin America Protein A Chromatography Resin by Country
8.1 Latin America Protein A Chromatography Resin Historic Market Size by Country
8.1.1 Latin America Protein A Chromatography Resin Market Size Growth Rate (CAGR) by Country: 2018 VS 2022 VS 2029
8.1.2 Latin America Protein A Chromatography Resin Sales in Volume by Country (2018-2023)
8.1.3 Latin America Protein A Chromatography Resin Sales in Value by Country (2018-2023)
8.2 Latin America Protein A Chromatography Resin Forecasted Market Size by Country
8.2.1 Latin America Protein A Chromatography Resin Sales in Volume by Country (2024-2029)
8.2.2 Latin America Protein A Chromatography Resin Sales in Value by Country (2024-2029)
9 Middle East and Africa Protein A Chromatography Resin by Country
9.1 Middle East and Africa Protein A Chromatography Resin Historic Market Size by Country
9.1.1 Middle East and Africa Protein A Chromatography Resin Market Size Growth Rate (CAGR) by Country: 2018 VS 2022 VS 2029
9.1.2 Middle East and Africa Protein A Chromatography Resin Sales in Volume by Country (2018-2023)
9.1.3 Middle East and Africa Protein A Chromatography Resin Sales in Value by Country (2018-2023)
9.2 Middle East and Africa Protein A Chromatography Resin Forecasted Market Size by Country
9.2.1 Middle East and Africa Protein A Chromatography Resin Sales in Volume by Country (2024-2029)
9.2.2 Middle East and Africa Protein A Chromatography Resin Sales in Value by Country (2024-2029)
10 Company Profiles
10.1 Merck KGaA
10.1.1 Merck KGaA Company Information
10.1.2 Merck KGaA Introduction and Business Overview
10.1.3 Merck KGaA Protein A Chromatography Resin Sales, Revenue and Gross Margin (2018-2023)
10.1.4 Merck KGaA Protein A Chromatography Resin Products Offered
10.1.5 Merck KGaA Recent Development
10.2 Tosoh Bioscience
10.2.1 Tosoh Bioscience Company Information
10.2.2 Tosoh Bioscience Introduction and Business Overview
10.2.3 Tosoh Bioscience Protein A Chromatography Resin Sales, Revenue and Gross Margin (2018-2023)
10.2.4 Tosoh Bioscience Protein A Chromatography Resin Products Offered
10.2.5 Tosoh Bioscience Recent Development
10.3 GE Healthcare
10.3.1 GE Healthcare Company Information
10.3.2 GE Healthcare Introduction and Business Overview
10.3.3 GE Healthcare Protein A Chromatography Resin Sales, Revenue and Gross Margin (2018-2023)
10.3.4 GE Healthcare Protein A Chromatography Resin Products Offered
10.3.5 GE Healthcare Recent Development
10.4 Bio-Rad Laboratories
10.4.1 Bio-Rad Laboratories Company Information
10.4.2 Bio-Rad Laboratories Introduction and Business Overview
10.4.3 Bio-Rad Laboratories Protein A Chromatography Resin Sales, Revenue and Gross Margin (2018-2023)
10.4.4 Bio-Rad Laboratories Protein A Chromatography Resin Products Offered
10.4.5 Bio-Rad Laboratories Recent Development
10.5 Thermo Fisher Scientific
10.5.1 Thermo Fisher Scientific Company Information
10.5.2 Thermo Fisher Scientific Introduction and Business Overview
10.5.3 Thermo Fisher Scientific Protein A Chromatography Resin Sales, Revenue and Gross Margin (2018-2023)
10.5.4 Thermo Fisher Scientific Protein A Chromatography Resin Products Offered
10.5.5 Thermo Fisher Scientific Recent Development
11 Upstream, Opportunities, Challenges, Risks and Influences Factors Analysis
11.1 Protein A Chromatography Resin Key Raw Materials
11.1.1 Key Raw Materials
11.1.2 Key Raw Materials Price
11.1.3 Raw Materials Key Suppliers
11.2 Manufacturing Cost Structure
11.2.1 Raw Materials
11.2.2 Labor Cost
11.2.3 Manufacturing Expenses
11.3 Protein A Chromatography Resin Industrial Chain Analysis
11.4 Protein A Chromatography Resin Market Dynamics
11.4.1 Protein A Chromatography Resin Industry Trends
11.4.2 Protein A Chromatography Resin Market Drivers
11.4.3 Protein A Chromatography Resin Market Challenges
11.4.4 Protein A Chromatography Resin Market Restraints
12 Market Strategy Analysis, Distributors
12.1 Sales Channel
12.2 Protein A Chromatography Resin Distributors
12.3 Protein A Chromatography Resin Downstream Customers
13 Research Findings and Conclusion
14 Appendix
14.1 Research Methodology
14.1.1 Methodology/Research Approach
14.1.2 Data Source
14.2 Author Details
14.3 Disclaimer

Published By : QY Research

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